U.S. Government Studies of BPA

For two decades, federal government scientists have conducted studies of BPA. These studies have confirmed the safety of BPA with in-depth research in three key areas:

  • Monitor exposure levels in the US population.
  • Understand the metabolism and elimination of BPA from the human body.
  • Assess if BPA is likely to cause any health effects.

Reviewing the extensive government research studies of BPA presented here will help you to understand why FDA is confident to answer the key question: “Is BPA safe?” with a clear answer – “Yes.”

2018
NTP

In the CLARITY Core study, BPA has very little potential to cause health effects

health Read Report
2016
NTP

Exposure of cashiers to BPA from handling receipts shown to be very low

exposure Read Report
2015
FDA

No neurological effect from developmental exposure to low doses of BPA in rodents

health Read Report
2015
FDA

Pharmacokinetic model developed for assessment of human exposure to BPA

metabolism Read Report
2015
NTP

Humans rapidly metabolize and eliminate BPA from the body

metabolism Read Report
2015
FDA

No evidence for biological effects in reproductive organs of rodents from developmental exposure to BPA

health Read Report
2014
FDA

No behavioral effects from developmental exposure to low doses of BPA in rodents

health Read Report
2014
FDA

Pharmacokinetic models are useful to extrapolate from rodent studies to humans

metabolism Read Report
2014
FDA

Little potential for low doses of BPA to act as an estrogen in rodents

metabolism Read Report
2014
FDA

No effects from developmental exposure to low doses of BPA in rodents

health Read Report
2013
2014
CDC

BPA exposure confirmed to be very low in U.S. population – 2013-2014

exposure Read Report
2013
FDA

Pharmacokinetic model developed for assessment of metabolism of BPA in neonatal and adult rodents

metabolism Read Report
2013
FDA

Metabolism of BPA demonstrated in maternal and fetal primates

metabolism Read Report
2012
FDA

No dose-related effects on behavior from developmental exposure to low doses of BPA in rodents

health Read Report
2012
FDA

Treatment-related neurological effect from developmental exposure of rodents to low doses of BPA could lead to effects on behavior

health Read Report
2012
FDA

Study in rodents reveals that BPA does not accumulate in the body

metabolism Read Report
2011
2012
CDC

BPA exposure confirmed to be very low in U.S. population – 2011-2012

exposure Read Report
2011
FDA

No early developmental effects from low dose exposure to BPA in rodents

health Read Report
2011
FDA

Pharmacokinetic model developed for assessment of metabolism of BPA in adult primates

metabolism Read Report
2011
FDA

BPA does not accumulate in fetal rodents and is limited maternal and fetal metabolism

metabolism Read Report
2011
FDA

Metabolism of BPA in neonatal primates is more efficient compared to neonatal rodents

metabolism Read Report
2010
FDA

Sensitive analytical methodology developed to support evaluation of BPA metabolism

metabolism Read Report
2010
FDA

Locational transfer of BPA to neonatal rodents is limited by efficient maternal metabolism

metabolism Read Report
2010
FDA

BPA is efficiently metabolized and quickly eliminated from neonatal and adult rodents

metabolism Read Report
2010
FDA

BPA is efficiently metabolized and quickly eliminated from neonatal and adult primates

metabolism Read Report
2010
EPA

No behavioral effects observed in rodents exposed to BPA during gestation

health Read Report
2009
2010
CDC

BPA exposure confirmed to be very low in U.S. population – 2009-2010

exposure Read Report
2008
EPA

No reproductive effects observed in rodents exposed to BPA during gestation

health Read Report
2007
2008
CDC

BPA exposure confirmed to be very low in U.S. population – 2007-2008

exposure Read Report
2005
2006
CDC

BPA exposure confirmed to be very low in U.S. population – 2005-2006

exposure Read Report
2003
2004
CDC

BPA exposure confirmed to be very low in U.S. population – 2003-2004

exposure Read Report