Reproductive Health - Basic Exploratory Research versus Guideline-Compliant Studies Used for Hazard Evaluation and Risk Assessment: Bisphenol A as a Case Study

Author: Rochelle W. Tyl

Publication: Reproductive and Developmental Health

Date: June 29, 2009

health

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What was tested?
This study provides an assessment of BPA guideline-compliant and exploratory research animal studies and describes BPA pharmacokinetics in rats and humans.
Findings
"Weight-of-evidence evaluations have consistently concluded that low-level BPA oral exposures do not adversely affect human developmental or reproductive health."
Study Limitations
None cited.
Importance
This article confirms the importance of relying on large-scale, guideline-compliant studies as opposed to basic research studies for risk assessment.